Obesity is a modern disease. But nature has already created a natural medication for curing this disease, millions of years back. The name of this is natural medication is Hoodia. How Hoodia is effective in obese? When was the anti obesity element first isolated? Who isolated the extract? At present, who got the license for manufacture of Hoodia? For these questions we can find answer in this article.

Hoodia is a cactus like plant seen in the great Kalahari Desert of South Africa. San Bushmen, the South Africa tribal people used to chew the leaves of this plant to suppress their hunger from times immemorial.

Many appetite suppressants and antiobesity drugs though effective are usually associated with side effects. But Hoodia has both qualities of a perfect medicine- efficiency and side effectiveness.

The South African council for Scientific and Industrial Research (CSIR) in 1977 extracted the appetite suppressant ingredient in Hoodia now known as P-57. the CSIR then approved a license to United Kingdom – based phytopharm.

Phytopharm in the year 1995 got the license to develop appetite suppressant from Hoodia plant. Rigorous research work was done to develop a highly effectual medication which will fit in the form of Hoodia diet pills, Hoodia capsules and Hoodia health drinks.

Initially phytopharm pooled resources with the phytopharm with the pharmaceutical company Pfizer to segregate active constituents from the extract and for preparing an effective antiobesity drug.

Pfizer returned the marketing rights to phytopharm in 2002 as they were unable to develop a p-57 molecule synthetically and economically. At present unilever has joined hands with phytopharm to market Hoodia diet pills as diet supplements in their diet food product line.

As Hoodia Gordonii is in such as a high demand, it is considered a protected plant and it can be exported with a special permit from the government of South Africa – a CITES permit.

There are three laboratory tests available to test the quality of extract in the drug available. They

1. Microscopy:

In this test, the sample of Hoodia is examined under a microscope (usually at 400x magnification). Pure Hoodia Gordonii would appear to have long fibers with whirled striations, so this helps in checking the purity of the sample.

2. High Performance Thin layer Chromatography (HPTLC).

3. High Performance Liquid Chromatography (HPLC).

These laboratory tests help in testing the purity of Hoodia sample.

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